个人简介

2022年6月于陕西师范大学获理学博士学位。2022年7月至2026年4月在陕西师范大学化学化工学院从事博士后研究工作，2026年4月任陕西师范大学化学化工学院副研究员。于2024年入选全国博士后管委会办公室和澳门科学技术协进会“澳门青年学者”计划，任澳门科技大学材料科学与工程研究院博士后研究员。主持国家自然科学基金青年项目、陕西省博士后基金、西安市青年人才托举计划A类项目等，参与多项国家自然科学基金项目。主要研究方向为单颗粒及单分子水平生物传感、数字式单颗粒医学诊断设备研发和中医药转化医学研究。部分研究成果已经发表于Nano Lett., Anal. Chem., Biosens. Bioelectron., Chem. Commun.等期刊。

代表性成果

2023-2026

1. Wenjiao Fan, Xinyu Yu, Tianyu Zhang, Wei Ren*, Hui Tian, and Chenghui Liu*. Single microbead floating/sinking-enabled digital biosensing. Nano Letters, 2026, 26, 4425-4431.

2. Junyue Sun, Xinrui Fei, Wenjiao Fan*, Wei Ren, Jing Zhang, and Chenghui Liu*. DNA hybridization-accelerated programmable immune-aggregation of microbeads enabling mix-and-read flow cytometric protein analysis. Analytical Chemistry，2025, 97, 13514-13521.

3. Wenjiao Fan, Wei Ren*, Dailu Jia, Jingjing Shi, and Chenghui Liu*. Digital-like enzyme inhibition mechanism-based strategy for the digital sensing of heparin-specific biomarkers. Analytical Chemistry, 2023, 95, 13690-13697.

4. Dailu Jia, Wenjiao Fan*, Wei Ren and Chenghui Liu*. Click chemical ligation-enabled digital particle counting for multiplexed microRNA analysis. Biosensors and Bioelectronics, 2024, 261, 116508.

5. Ruo Ma, Wenjiao Fan*, Yueran Wang, Xinrui Fei and Chenghui*. Enzyme inhibition-enabled CRISPR/Cas12a biosensing system for heparin-related non-nucleic acid biomarkers. Chemical Communications, 2025, 61, 13421-13424.

6. Jie Liu, Jingjing Shi, Qinya Feng, Wenjiao Fan* and Chenghui Liu*. An immunoassay-like recognition mechanism-based lateral flow strategy for rapid microRNA analysis. Chemical Communications, 2023, 59, 11851-11854.

7. Wenjiao Fan, Yuanyuan Dong, Wei Ren* and Chenghui Liu*. Single microentity analysis-based ultrasensitive bioassays: Recent advances, applications, and perspectives. Trends in Analytical Chemistry, 2023, 162, 117035.

8. Wenjiao Fan, Wei Ren and Chenghui Liu*. Advances in optical counting and imaging of micro/nano single‑entity reactors for biomolecular analysis. Analytical and Bioanalytical Chemistry, 2023, 415, 97-117.

9. Wenjiao Fan, Xing Lu, Jianman Wang and Yao He*. Nanotechnologies for traditional Chinese medicine research: quality control and therapeutic applications. Nanoscale, 2025, 17, 27151-27171.

10. 范文娇，任伟*，董园园，刘成辉*. 流式微球技术在生命分析化学领域的研究进展. 中国科学：化学, 2024, 54, 1800-1816.

11. Zhengkun Dong, Wenjiao Fan*, Wei Ren and Chenghui Liu*. Bead-enriched catalyzed hairpin assembly for the flow cytometric detection of microRNA via FRET signal readout. Sensors & Diagnostics, 2024, 3, 112-116.

2018-2022

1. Wenjiao Fan, Pihua Han, Qinya Feng, Yuanyuan Sun, Wei Ren, Thomas Lawson and Chenghui Liu*. Nucleic acid substrate-independent DNA polymerization on exosome membrane: Mechanism study and application in exosome analysis. Analytical Chemistry，2022，94, 2172-2179.

2. Wenjiao Fan, Yan Qi, Liying Qiu, Pan He, Chenghui Liu* and Zhengping Li. Click chemical ligation-initiated on-bead DNA polymerization for the sensitive flow cytometric detection of 3′-Terminal 2′-O-methylated plant microRNA. Analytical Chemistry, 2018, 90, 5390-5397.

3. Wenjiao Fan, Yan Qi, Xiaohui Lu, Wei Ren, Chenghui Liu* and Zhengping Li. An emulsion-free digital flow cytometric platform for the precise quantification of microRNA based on single molecule extension-illuminated microbeads (dFlowSeim). Chemical Communications, 2020, 56, 7179-7182.

4. Wenjiao Fan, Dou Liu, Wei Ren* and Chenghui Liu*. Trends of bead counting-based technologies toward the detection of disease-related biomarkers. Frontiers in Chemistry, 2020, 8, 1208-1214.

5. Wenjiao Fan, Wei Ren*, Liping Zhu and Chenghui Liu*. On-bead enzyme-catalyzed signal amplification for the high-sensitive detection of disease biomarkers. Methods in Enzymology, 2020, 630, 179-197.